ED Secondary to Treatment for Localized Prostate Cancer

ED Secondary to Treatment for Localized Prostate Cancer

Previous Page In This ArticleAbstract and IntroductionPathophysiology of Erectile DysfunctionRadiation TherapyCryotherapyRadical ProstatectomyTreatmentConclusionsTablesReferencesRelated Links

Conclusions

Despite significant advances in the management of localized prostate cancer, ED remains a common problem. However, several therapies are available. For every patient complaining of ED after being treated for clinically localized cancer prostate there is at least one potentially efficacious therapeutic alternative. Treatment should begin with oral drugs or intraurethral drug administration. Additional options include vacuum erection devices and intracavernous injection. Combinations of oral with intraurethral and/or intracavernous injections also may be effective.

Interventions to address treatment-induced impotence should start as early as possible to minimize anxiety and depression, which are common symptoms in patients with prostate cancer. It is likely that early introduction of medical therapy, particularly intracorporal injections, has resulted in a higher incidence of spontaneous return of erections.

The ideal pharmacotherapeutic agent is not yet available. Such a drug should be able to produce recovery of the endothelial and neurogenic potential to produce nitric oxide and thus erection and should provide on demand a sustained and reproducible penile erection with minimal side effects.Reprint Address

Address reprint requests to Cláudio Telöken, MD, PhD, Department of Urology, Fund Fac Federal Ciencias Medicas, cep 90480-003, Porto Alegre, Brazil. E-mail: cteloken@hotmail.comPrevious PageSection 7 of 7 
Cancer Control.  2001;8(6):540-545.  ©2001 H. Lee Moffitt Cancer Center and Research Institute, Inc.


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